Is taking 2 different kinds of allergy medicine at the same time harmful?

my boyfriend took 2 pills of benadryl and 1 pill of aprodine. i'm worried that the two might have a bad reaction with each other and harm him. somebody please help me!

There isn't an interaction between the two, but taking Codeine (aprodine) with Diphenhydramine (benadryl) should make him fairly loopy. He will probably just go to sleep.

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