How does cholesterol contribute to atherosclerosis?

Many scientists believe atherosclerosis begins because the innermost layer of the artery (endothelium) becomes damaged. As a result, over time fats, cholesterol, fibrin, platelets, cellular debris and calcium are deposited in the artery wall. Gradually these substances build up and even- tually narrow and block the artery, similar to scale forming on the insides of pipes.

Three of the possible causes of damage to the arterial walls are: 1) elevated levels of cholesterol and triglyceride in the blood, 2) high blood pressure and 3) cigarette smoke. Cigarette smoke particulady aggravates and accelerates the development of atherosclerosis in the coronary arteries, aorta and arteries of the legs.

Atherosclerosis is when your arteries become filled with "placques" , this makes it more difficult for blood to flow throught the artery because it is now thinner. Cholesterol is a substance that can cause these "placques" and lead to atherosclerosis.