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What will happen if you give someone a blood transfusion with a different blood type than their own?



this must've happened a lot back in the day when they didn't know about blood types.

There are basically the following blood types A, B, AB and O, as well as the Rh factors + and -. This means that a person with A blood has a marker for A antigen and a person with B blood has a marker for B antigen. AB has both A & B antigens. O have no antigens. In order for blood to be compatible, the blood must be able to be given to someone who has their same marker or who is missing any marker. Universal donor is O negative blood. That person can give to all recipients. (It means no A or B, and no Rh factor). Universal recipient is AB pos. That recipient has both A B and Rh pos and can receive blood from all donors. If a person gets mismatched blood, it is like giving that person a huge antigen insult, and can throw them into shock and they can possibly die from it. So, to prevent this, a small amount of the donor and recipient's blood are actually pooled together to see if clumping occurs (clumping indicates it is not compatible), in the lab, before it is sent to the patient recipient to get the donor's blood. If the two are compatible, it is relatively safe to give it to the recipient. There are exceptions, but this is generally the way crossmatching blood works for transfusions. Hope this helps. Source(s): MD
Before blood typing, blood transfusions failed - and often took the patient out (meaning death) with it.
There was a girl who was accidentally given the wrong blood type in a hospital a couple years ago and her blood coagulated in a matter of hours, killing her.

All they could do was make her comfortable.

She would have survived the original reason she was in the hospital but the transfusion killed her.

It depends on the two types being mixed.

Some are compatible and some are not.
a severe reaction sets in and if the mismatch is of ABO blood groups then its fatal.
Rh reactions are not serious the first time but are as severe the second time.

During past when they did this the person would always die due to the mismatch reaction.
They would likely die.
o negative it doesnt matter i dont think, because it is compatiable with all blood types
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