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How does actos help in controlling my diabetes?


I just need some info on the tablet that was added to my other meds that i was already taking.

Pioglitazone is an anti-diabetic drug (thiazolidinedione-type, also called "glitazones") used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes (non-insulin-dependent diabetes). It works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.

Pioglitazone is used either alone or in combination with other anti-diabetic medications (e.g., metformin, sulfonylureas, insulin).

And now the rest of the story:

The "glitazone" diabetes drugs Actos and Avandia may double or triple the risk of broken bones after a year or two of use.

The finding comes from Swiss researchers who analyzed 12 years of data on U.K. diabetes patients. They compared the 1,020 patients who suffered some kind of fracture to 3,728 matched patients who did not break any bones.

Over the course of the study, most of the patients took several diabetes drugs. But those who refilled their Actos or Avandia prescriptions eight times or more -- about 12 to 18 months of use -- had nearly twice the fracture risk of other patients.

And those who refilled their Actos or Avandia prescriptions 15 times or more -- two or more years of treatment -- nearly tripled their risk of fracture, found Christophe R. Meier, PhD, head of pharmacoepidemiology research at University Hospital Basel, Switzerland, and colleagues.

Also related heart disease>>>>

Actos has a very complex mechanism of action and will only work in the presence of insulin. To put it too simply, it helps sensitize your body to the insulin that your pancreas secretes. When the tissues in your body have been exposed to high glucose levels, they are also exposed to abnormal amounts of insulin (body's response to decrease glucose levels). After some time, the tissues become less sensitive to the the glucose-lowering effects of insulin. This medication will help control your blood glucose by sensitizing those tissues to insulin. Actos will lower your hemoglobin A1c, but not by much.

Hi Rosie

There is an article you probably want to check

In the article they 're reviewing the TOP 5 鈥淩esources for Diabetes Care"

To qualify them, they have selected 3 basic criteria:

1. Quality Content
2. Useful Information
3. Valuable Tips

You probably will find some resources more interesting and useful than others. But in general terms they all provide very valuable information which I believe really worth considering. Click the link below to find out more

Hope you find useful, Good luck

Actos helps your pancreas control your sugar. It worked for me wonderfully, but it causes me to retain fluid, so I can't take it. If you begin to retain water, your feet or legs start swelling - talk to your doctor. This is one of the best diabetic controller, but the side effects keep some of us from using it.

all anti diabetes medicines either stimulate the insulin secreting cells or the use age of sugar in the periphery is made available or also the digestion of sugar is prevented ---you have given only the commercial name --- pharmacological name to disclosed

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