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What is the difference between type 1 and 2 diabetes?



What is the difference between type 1 and 2 diabetes?

Type 1 diabetes is an auto-immune disease where the body's immune system destroys the insulin-producing beta cells in the pancreas. This type of diabetes, also known as juvenile-onset diabetes, accounts for 10-15% of all people with the disease. It can appear at any age, although commonly under 40, and is triggered by environmental factors such as viruses, diet or chemicals in people genetically predisposed. To live, people with type 1 diabetes must inject themselves with insulin several times a day and follow a careful diet and exercise plan.

Type 2 diabetes is the most common form of diabetes, affecting 85-90% of all people with the disease. This type of diabetes, also known as late-onset diabetes, is characterised by insulin resistance and relative insulin deficiency. The disease is strongly genetic in origin but lifestyle factors such as excess weight, inactivity, high blood pressure and poor diet are major risk factors for its development. Symptoms may not show for many years and, by the time they appear, significant problems may have developed. People with type 2 diabetes are twice as likely to suffer cardiovascular disease. Type 2 diabetes may be treated by dietary changes, exercise and/or tablets. Insulin injections may later be required. Source(s): http://www.healthinsite.gov.au/topics/ty...
check out the site it tells you.
http://www.healthinsite.gov.au/topics/ty...
Hi,
Type I is known as IDDM i.e Insulin Dependent Diabetes Mellitus. It is due to deficiency of Insulin. The insulin is not able to synthesize in proper amount or there is a damage in the beta cells of Islet of Langerhans present in Pancreas.
Type II is NIDDM i.e. Non - Insulin Dependent Diabetes Mellitus. In this case the Insulin may be availabe to the body but due to deficiency of some intrinsic factor it is not active or it is not able to make the glucose ulilize by the body cells.
Living With Diabetes :
> Diabetes Simplified
http://www.watchtower.org/library/g/2003...
The first answerer did very well but I should clarify about "insulin resistance" in type 2. The body's cells have receptors on their surface for insulin. When insulin attaches to its receptor, the response is that the cell takes in glucose from the surrouding fluid. In type 2 diabetes, the cells are less responsive to insulin and so they take in less glucose and so the amount of glucose in the extracellular fluid is higher than it should be. The pancreas detects this higher glucose level and responds to it by secreting more insulin.

So in type 2 diabetes the insulin level in blood is high, whereas in type 1 it is low.
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