63 year old alcoholic taken to the er w/gangrene in both feet;He is stuporous;had a siezure during evening of transfer and was treated with phnytoin&bartituates;by nighttime he was noted to have opisthotonic posturing;developed increasing rigor,resp.distress and unresponsiveness;70/30mm Hg; HR110bpm,resp.rate40/min;recta... temp41.7 C;marked trismus;The neck was stiff and hyper extended; nectrotic blackened areas over both feet;several draining ulcers on heels and toes; neurologically the patient responded to deep pain w/a grimace. After specific therapy & supportive care was initiated the patient ultimately recovered. What is the etiology of infection?; What virulence factor produced by etiologic agent of his infection was responsible for his trismus?;How did the patient become infected with this organism?;what was the role of his gangrenous feet in the development of this infection?;What is the specific therapy used to reat this infection?;How might this infection have been prevented? |
