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| *Women health>>>Diabetes |
In Type II diabetes, cells throughout the body are resistant to insulin鈥檚 uptake..? |
In Type II diabetes, cells throughout the body are resistant to insulin鈥檚 uptake why do then they are given insulin injection or tablets? Tablets can improve the way your own insulin works (metformin, glitazones), or make you produce more insulin to overcome the resistance (sulphonylureas) -in the latter case, think of it in this way: in a healthy person, insulin has 100% effect in peripheral tissues. In an insulin resistant person (the main underlying pathology in Type 2 Diabetes) this insulin only has 50% effect in tissues. So, if you have 200% of normal insulin level circulating in your blood, you will achieve the same desired 100% effect. Likewise with insulin injections. However, it is not that easy as high insulin levels also damage pancreas and limit your own ability to produce insulin, so giving more insulin is a road to nowhere. Insulin resistance is directly linked to obesity, or at least overweight, with the exeption of very rare genetic disorders, so the best way is to use the insulin sensitisers (the first group of drugs I mentioned) and lose some weight, even if you have only 5 kg extra around your waist! Hope this helps. Source(s): MD degree with PhD. in diabetes and nutrition Type 2 just means the insulin doesn't work as well as it should because of age, history, lifestyle etc. The tablets and injections either act as a source of more efficient insulin or they boost the insulin the person already produces so the insulin can do it's job better. Student Nurse (Registered Nursing) "Type 2 diabetes is a disease in which your pancreas does not produce enough insulin, or your body does not properly use the insulin it makes. If you have type 2 diabetes, glucose builds up in your blood instead of being used for energy. Type 2 diabetes is controlled through exercise and meal planning and may require medications and/or insulin to assist the body in making or using insulin more effectively." - Cdn Diabetes Assoc.com In my case, my body doesn't use the insulin it makes naturally. I am on 2 different types of insulin injections. I know it sounds crazy, if I have insulin I'm not using why take more....the answer I have from the doctor is the injected insulin is easier for my body to use than the natural insulin and it gives my body a break from trying so hard to keep making more and more insulin because my sugar is high. My glands don't know that I'm not using what's being made naturally. All the glands know is high sugar equals make more insulin...sooner or later your body will give out and not be able to keep up with that rate of insulin production...supplementing with injections makes your sugar go down and then you glands say, hey....we can take a break...she has enough insulin right now. My goal is to get off the injections in time and for that I will need my body to be capable of still making it's own insulin.. Please visit this site, I hope you will get good answers.http://thediabeteszone.com/ |
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