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What are the causes of estrogen deficiency in premenopausal women?

What are the causes of estrogen deficiency in premenopausal women?

The causes of estrogen deficiency in premenopausal women include
1. surgery / trauma / radiation destroying the ovaries
2. disease infection (TB/Leprosy) cancer destroying the ovaries
3. pituitary diseases mainly tumors like prolactinomas damaging cells that produce the hormone that cause the ovaries to function
4. Sheehan's Syndrome where the blood pressure drops after a delivery of a baby from excessive bleeding and parts of the pituitary dies from lack of blood flow.
5. brain trauma severing the connections within the hypothalamus that control pituitary function or severing the blood vessels that carry hormones from the hypothalamus to the pituitary
6. outside hormones / medications / poisons
Old OB/GYN Doc

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