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Cystic Fibrosis / Genetic Disorders Testing?


Hi. I know that these are optional tests, and I know that it is completely up to each individual as to whether or not she elects to have them done. My question is, if I have done the cystic fibrosis testing with my last daughter, is there any reason to do it again? I'm wondering if I am correct in thinking that it tests whether or not you are a carrier for the disease. If this is true, and it was negative before, is it possible to receive different results with my current pregnancy? Thanks so much for your help.

Testing is done for each pregnancy since the chance of CF gene would be different for each pregancy.

If only one parent is a carrier of a defective CF gene, the child will not have CF. But there is a 50% (1-in-2) chance that the child will be a CF carrier.

If both parents are carriers, there is a 25% (1-in-4) chance that the child will have CF, but a 50% chance that the child will be a carrier.

If you know you are not a carrier then your baby can't be born with CF.

I'm not sure what tests you are talking about. Were you tested, or was your daughter?
Do you have cystic fibrosis? Do you know for sure if you're a carrier?
If you have a family history for CF, and you tested your first child when she was in utero, then yes you should test the next child. If you are a carrier and your partner is a carrier, you have a 25% chance of having a child with cystic fibrosis EACH pregnancy. (You have a 50% chance of having a carrier, and 25% chance of having a child who has received neither gene from you both).

So yes, it is possible to have different results with your current pregnancy.

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