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| *Women health>>>Lupus |
Does anyone know anything about neonatal lupus? |
My daughter has neonatal lupus I have done some shadowing in the Neonatal Intensive Care Unit in the local Children's Hospital, but I do not remember seeing a case of this. I did some reading and found some information for you that I hope will help. From WebMD: Neonatal lupus is a rare autoimmune disorder that is present at birth (congenital). Affected infants often develop a characteristic red rash or skin eruption. In addition, infants with neonatal lupus may develop liver disease, a heart condition known as congenital heart block, and/or low numbers of circulating blood platelets that assist in blood clotting functions (thrombocytopenia). The symptoms associated with neonatal lupus, with the exception of congenital heart block, usually resolve within the first several months of life. The exact cause of neonatal lupus is unknown, although researchers speculate that specific antibodies that travel from a pregnant woman to her developing fetus via the placenta play a significant role. Neonatal lupus is not the infant form of lupus (systemic lupus erythematosus) although the skin rash resembles the one associated with lupus. Neonatal lupus is a separate disorder. The Research Registry for Neonatal Lupus, at http://www.neonatallupus.com/ , sounds like another good place to start and see what you can find from some of the contacts there. One last place to check out (there are a lot more...you could stay up all night reading this stuff!) is the eMedicine site linked below. It is way more scientific, but very informative. Neonatal lupus erythematosus (NLE) is a rare disorder caused by the transplacental passage of maternal autoantibodies. Only 1% of infants with positive maternal autoantibodies develop NLE. The most common clinical manifestations are cardiac, dermatologic, and hepatic. Some infants may also have hematologic abnormalities. Most mothers at the time of childbirth are healthy and without signs or symptoms of lupus erythematosus or other collagen vascular disorders. Mothers of children with NLE may later develop an atypical rather than classic picture of systemic lupus erythematosus (SLE) or other connective tissue disorder. If a mother with anti-Ro autoantibodies has 1 child with NLE, the incidence in subsequent pregnancies is approximately 25%. The incidence of congenital heart block is 15-30% in infants with NLE. I pray your daughter is comfortable and healthy and can come home soon! :) Source(s): http://www.webmd.com/hw/raising_a_family... http://www.neonatallupus.com/ http://www.emedicine.com/derm/topic807.h... |
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