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If a stroke is treated within one hour of onset, what therapies/drugs are used to treat it?


If a stroke is treated within one hour of onset, what therapies/drugs are used to treat it?

Ischemic strokes, the most common strokes, can be treated with a drug called tPA which dissolves artery-obstructing clots. The window of opportunity to use tPA to treat stroke patients is three hours, but to be evaluated and receive treatment, patients need to get to the hospital within 60 minutes. Stroke patients who received tPA within three hours of the onset of stroke symptoms are at least 30% more likely than placebo patients to recover from their stroke with little or no disability after three months.

tPA is a drug used to treat specifically heart attacks, rather than strokes per se. The FDA recommends that recent stroke victims or people with high blood pressure or a bleeding/haemorrhaging problem, should avoid it. As it is used a treatment for reducing cardiac blood clots, it wasn't commonly used against clots in the brain (stroke proper), but is now recommended for this purpose.

Essentially, it really matters whether it is due to a clot (thrombotic/embolic) or if it is a haemorrhage (burst vessel). This is what decides the drug treatment.

First One Must Discern Whether it is Embolic (~80%) or Hemorrhagic (~20%), if Embolic, Clot Busters and Interventional Radiology.

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